B1 VITAMIN B1 HCL
adenine phosphate
CAS: 70700-30-0;52175-10-7
Molecular Formula: C5H8N5O4P
B1 VITAMIN B1 HCL - Names and Identifiers
| Name | adenine phosphate |
| Synonyms | B2 VITAMIN B2 VITAMIN B6 USP AD3 VITAMIN AD3 B1 VITAMIN B1 HCL adenine phosphate VITAMIN A PALMITIAT 6-AMINOPURINE PHOSPHATE Adenine Purine phosphate 6-Aminopurine phosphate salt 6-AMINOPURINEPHOSPHATE(ADENINEPHOSPHATE) |
| CAS | 70700-30-0 52175-10-7 |
| EINECS | 633-221-1 |
| InChI | InChI=1/C5H5N5.H3O4P/c6-4-3-5(9-1-7-3)10-2-8-4;1-5(2,3)4/h1-2H,(H3,6,7,8,9,10);(H3,1,2,3,4) |
B1 VITAMIN B1 HCL - Physico-chemical Properties
| Molecular Formula | C5H8N5O4P |
| Molar Mass | 233.12 |
| Melting Point | 261-263℃ |
| Boling Point | 553.5°C at 760 mmHg |
| Flash Point | 322.7°C |
| Vapor Presure | 2.71E-12mmHg at 25°C |
| Appearance | White crystalline powder |
| Storage Condition | Keep in dark place,Inert atmosphere,Room temperature |
| Sensitive | Sensitive to light |
| MDL | MFCD00035170 |
| Physical and Chemical Properties | White powder. Melting point 261-263 °c (decomposition). Soluble in boiling water, micro-soluble in cold water, insoluble in chloroform and ether. Tasteless. |
| Use | For the prevention and treatment of leukopenia caused by various reasons, especially for leukopenia caused by tumor chemotherapy |
B1 VITAMIN B1 HCL - Risk and Safety
| Hazard Symbols | Xn - Harmful |
| Risk Codes | 22 - Harmful if swallowed |
| Safety Description | 36 - Wear suitable protective clothing. |
B1 VITAMIN B1 HCL - Nature
Open Data Verified Data
- This product is a 6 amino purine phosphate, white crystalline powder; Taste acid. Slightly soluble in water, insoluble in ethanol or chloroform, dissolved in boiling water or sodium hydroxide solution, slightly soluble in dilute hydrochloric acid. The melting point was 360-365 °c.
- the active part of the nucleic acid and some coenzyme of this strain participates in the metabolic function of the organism, can maintain the ATP level in the red blood cells, and prolong the survival time of the red blood cells stored in the blood. It can stimulate the proliferation of leukocytes.
Last Update：2024-01-02 23:10:35
B1 VITAMIN B1 HCL - Preparation Method
Open Data Verified Data
- a synthesis method using hypoxanthine as a raw material.
- a synthesis method using diethyl malonate as a raw material.
Last Update：2022-01-01 11:12:22
B1 VITAMIN B1 HCL - Introduction
The taste is slightly sour. Soluble in boiling water and sodium hydroxide solution, slightly soluble in cold water, dilute hydrochloric acid, insoluble in ethanol and chloroform. At pH2, the maximum absorption wavelength is 262 · 5nm(ε13200), the minimum absorption wavelength is 229nm, the absorbance ratio A250/A260 = 0 · 76, A280/A260 = 0 · 38, A290/A260 = 0 · 04. Half lethal dose (mice, oral) 750mg/kg.
Last Update：2022-10-16 17:28:06
B1 VITAMIN B1 HCL - Use
Open Data Verified Data
- It is used for the prevention and treatment of leukopenia caused by various causes, especially leukopenia caused by tumor chemotherapy, radiotherapy and benzene drug poisoning. This product is often used with hormones or other vitamins and other drugs and blood transfusion.
- tablet content 90%-11o. o%(labeled amount) (Shanghai o/ws 1 704 80)
- usage and dose of oral, intramuscular or intravenous injection, Daily 20~60mg. This product is widely used in blood storage, can maintain the ATP level in red blood cells, prolong the survival time of red blood cells in the stored blood.
Last Update：2022-01-01 11:12:22
B1 VITAMIN B1 HCL - Safety
Open Data Verified Data
light shielding, closed storage.
Last Update：2022-01-01 11:12:22
B1 VITAMIN B1 HCL - Reference Information
| Introduction | adenine phosphate drugs are a class of new drugs against metabolic bone diseases developed in recent 20 years, is a pyrophosphate analog, is the P-O-P bond in the latter is replaced by the P-C-P bond, for the treatment of osteoporosis, osteoarthritis, and multiple myeloma (MM), various bone metabolic diseases such as hypercalcemia and bone pain caused by bone metastasis of malignant tumor. |
| uses | adenine phosphate is the active part of nucleic acids and some co-enzymes involved in metabolic functions in living organisms, it can maintain the ATP level in red blood cells and prolong the survival time of red blood cells in stored blood. It can stimulate the proliferation of leukocytes. It is used for leukopenia caused by various reasons, especially leukopenia caused by tumor chemotherapy, radiotherapy and benzene poisoning. This product is often used in combination with hormones or other vitamins and blood transfusion. |
| properties | White needle-like crystals. 220 ° C began to sublimate, 360-365 ° C decomposition. Soluble in acid and alkali, slightly soluble in alcohol, insoluble in ether and chloroform. The aqueous solution was neutral. Has a strong salty taste. |
| preparation method | Vitamin B4 is obtained by ammoniating 4, 6-dichloro-5-nitropyrimidine with ammonia water, 6-diamino-5-nitropyrimidine is obtained by cyclization together with formic acid, formamide and sodium thiosulfate. |
| production method | Adenine is obtained by salt formation. Add adenine to distilled water, heat to boiling, add phosphoric acid to pH1-2 with stirring, make it completely soluble, decolorize with activated carbon for 0.5h, filter, repeat decolorizing again, cool the filtrate to crystallize, filter, the crystals were washed with distilled water and once with ethanol. Dry, adenine phosphate (Vitamin B4). Adenine was produced by fermentation of glutamic acid. The mother liquid of glutamic acid was adsorbed with × 7 cation exchange resin, and the first part of the eluent was collected, acidified and filtered to remove impurities, then adsorbed with 001 × 7 resin, eluted with pH7-12 N sodium hydroxide, concentrated, and crystallized to obtain adenine crude product. Add water to dissolve, adjust pH to 1-2 with phosphoric acid, decolorize and filter to obtain crude adenine phosphate. After crystallization, refined, dried vitamin B4. |
Last Update：2024-04-10 22:29:15
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Spot supply
Product Name: Adenosine Impurity 1 Phosphate（Adenosine EP Impurity A Phosphate） Visit Supplier Webpage Request for quotationCAS: 70700-30-0
Tel: 0714-3999186
Email: 2853786052@qq.com
Mobile: 86+15671228036
QQ: 2853786052
Wechat: 15671228036
Multiple SpecificationsSpot supply
Product Name: VB4 Visit Supplier Webpage Request for quotationCAS: 70700-30-0
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
Wechat: 18301782025
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